Product Name	Recombinant Rabbit Anti-MMP13 Monoclonal Antibody
Cat No.	SLA0857M
Chinese Name	基质金属蛋白酶13重组兔单抗
Alias	CLG3; MANDP1; MDST; MMP-13; Clg; Mmp1; MMP13_HUMAN; MMP13; Matrix metalloproteinase-13 (MMP-13); 3.4.24.-; MMP13_MOUSE; MMP13_RAT; UMRCASE; matrix metallopeptidase 13; matrix metalloproteinase 13 (collagenase 3); collagenase 3
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	4C4
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human MMP13
Purification	affinity purified by Protein A
Concentration	1mg/ml
Observed MW.	60 kDa
Subcellular Location	Extracellular
Gene ID	4322
Swiss-Prot	P45452
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	bs-0575P is one synthetic peptide derived from human MMP13. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008].
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.