Product Name	Recombinant Rabbit Anti-CDK5 Monoclonal Antibody
Cat No.	SLA0390M
Chinese Name	周期素依赖性激酶5单克隆抗体
Alias	LIS7; PSSALRE; Crk6; CDK5_HUMAN; CDK5; Cell division protein kinase 5; Cyclin-dependent-like kinase 5; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit (TPKII catalytic subunit); 2.7.11.1; CDKN5; CDK5_MOUSE; cyclin dependent kinase 5
Host Species	Mouse
Isotype	IgG1
Clonality	Monoclonal
Clone No.	1D8
React Species	Human
Applications	WB (1:500-2000) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human CDK5(N-terminus)
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	33 kDa
Observed MW.	34 kDa
Subcellular Location	Nucleus
Gene ID	1020
Swiss-Prot	Q00535
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.