Product Name	Recombinant Rabbit Anti-GP1BA Monoclonal Antibody
Cat No.	SLA0360M
Alias	BDPLT1; BDPLT3; BSS; CD42B; CD42b-alpha; DBPLT3; GP1B; GPIbA; GPIbalpha; VWDP; GP1BA_HUMAN; GP1BA; GP-Ib alpha; GPIb-alpha; Glycoprotein Ibalpha; Antigen CD42b-alpha; glycoprotein Ib platelet subunit alpha; glycoprotein Ib (platelet), alpha polypeptide; human platelet antigen 2; platelet glycoprotein Ib alpha chain
Host Species	Mouse
Isotype	IgG1
Clonality	Monoclonal
React Species	Human
Applications	Flow-Cyt (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human CD42b
Purification	affinity purified by Protein G
Subcellular Location	Membrane
Gene ID	2811
Swiss-Prot	P07359
Storage	0.01M PBS (pH7.4). Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq, Mar 2010].
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.