Product Name	Recombinant Rabbit Anti-ENG Monoclonal Antibody
Cat No.	SLA0371M
Chinese Name	人CD105单克隆抗体
Alias	END; HHT1; ORW1; EGLN_HUMAN; ENG; EGLN_MOUSE; Cell surface MJ7/18 antigen; Edg; CD105; Endo; S-endoglin; endoglin; Osler-Rendu-Weber syndrome 1
Host Species	Mouse
Isotype	Mouse IgG1, k
Clonality	Monoclonal
Clone No.	3C8
React Species	Human
Applications	Flow-Cyt (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein G
Predicted MW.	70 kDa
Observed MW.	90 kDa
Subcellular Location	Membrane
Storage	0.01M PBS (pH7.4). Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.