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Product Name Recombinant Rabbit Anti-PRKCD Monoclonal Antibody Cat No. SLA3035M Chinese Name 磷酸化蛋白激酶C亚性D型重组兔单抗 Alias ALPS3; CVID9; MAY1; PKCD; nPKC-delta; D14Ertd420e; PKC[d]; PKCdelta; KPCD_HUMAN; PRKCD; Tyrosine-protein kinase PRKCD; 2.7.11.13; KPCD_MOUSE; KPCD_RAT; protein kinase C delta; protein kinase C, delta; PRKCD | PKC delta (phospho-Y313); p-PKC delta; phospho-PKC delta; p-PRKCD; PRKCD | PKC delta (phospho-Tyr313) Host Species Rabbit Isotype IgG Clonality Monoclonal Clone No. 4F4 React Species Human Applications WB (1:500-2000)
IP (1:20-50)
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.Immunogen A synthesized peptide derived from human PKC delta around the phosphorylation site of Y313 Purification affinity purified by Protein A Predicted MW. 78 kDa Observed MW. 75 kDa Subcellular Location Nucleus Gene ID 5580 Swiss-Prot Q05655 Storage 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.Background Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression as well as survival of several cancers, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.
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