Product Name	F11R | JAM-A/CD321 Recombinant Rabbit mAb
Cat No.	SLM-52561R
Chinese Name	连接粘附分子1重组兔单抗
Alias	CD321; JAM; JAM1; JAMA; JCAM; KAT; PAM-1; 9130004G24; ESTM33; JAM-1; JAM-A; Jcam1; Ly106; JAM1_HUMAN; F11R; Junctional adhesion molecule 1 (JAM-1); Platelet F11 receptor; Platelet adhesion molecule 1 (PAM-1); JAM1_MOUSE; F11 receptor; junctional adhesion molecule 1
Host Species	Rabbit
Isotype	IgG
Clonality	Recombinant
Clone No.	7E1F
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human JAM A
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	30 kDa
Observed MW.	40 kDa
Subcellular Location	Membrane
Gene ID	50848
Swiss-Prot	Q9Y624
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Junctional Adhesion Molecule 1 (JAM1) seems to play a role in epithelial tight junction formation. It appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. JAM1 plays a role in regulating monocyte transmigration involved in integrity of the epithelial barrier. JAM1 is also involved in platelet activation.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.