Product Name	Recombinant Rabbit Anti-TGFBR1 Monoclonal Antibody
Cat No.	SLA3297M
Alias	AAT5; ACVRLK4; ALK-5; ALK5; ESS1; LDS1; LDS1A; LDS2A; MSSE; SKR4; TBR-i; TBRI; TGFR-1; tbetaR-I; ESK2; TbetaRI; TGFR1_BOVIN; TGFBR1; TGF-beta type I receptor; Transforming growth factor-beta receptor type I (TGF-beta receptor type I | TbetaR-I); 2.7.11.30; TGFR1_HUMAN; Activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5 (ALK-5 | ALK5); Serine/threonine-protein kinase receptor R4 (SKR4); TGFR1_MOUSE; TGFR1_RAT; transforming growth factor beta receptor 1; multiple self-healing squamous epithelioma; transforming growth factor beta receptor I; activin A receptor type II-like kinase, 53kDa; TGF-beta receptor type-1; Activin receptor-like kinase 5; Serine/threonine-protein kinase receptor R4; Transfor
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	11D0
React Species	Human
Applications	WB (1:500-2000) IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) ELISA (1:5000-10000) IP (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Subcellular Location	Membrane
Gene ID	7046
Swiss-Prot	P36897
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.