Product Name	Recombinant Rabbit Anti-TK1 Monoclonal Antibody
Cat No.	SLA0859M
Chinese Name	胸苷激酶1重组兔单抗
Alias	TK2; KITH_HUMAN; TK1; 2.7.1.21; thymidine kinase 1; thymidine kinase 1, soluble; cytosolic thymidine kinase
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	9C1
React Species	Human
Applications	WB (1:500-2000) Flow-Cyt (1:50-100) ICC/IF (1:50-100) IP (1:20-50) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human Thymidine kinase
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	25 kDa
Observed MW.	25 kDa
Subcellular Location	Cytoplasm
Gene ID	7083
Swiss-Prot	P04183
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells. Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5'-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA. Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is is also used to select hybridoma cell lines in the production of monoclonal antibodies. Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division. Because of this, Thymidine Kinase can be used as a proliferation marker in the diagnosis, treatment, and follow-up of malignant diseases, especially hematological malignancies. Thymidine Kinase may be observed as a monomer, dimer, trimer or tetramer.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.