Product Name	Recombinant Rabbit Anti-ABRAXAS1 Monoclonal Antibody
Cat No.	SLA2478M
Chinese Name	ABRAXAS1重组兔单抗
Alias	ABRA1; CCDC98; FAM175A; ABRX1_HUMAN; ABRAXAS1; Coiled-coil domain-containing protein 98; Protein FAM175A; abraxas 1, BRCA1 A complex subunit; coiled-coil domain containing 98; family with sequence similarity 175, member A; family with sequence similarity 175 member A; Abraxas protein
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	7C3
React Species	Human
Applications	WB (1:500-2000) Flow-Cyt (1:50-100) ICC/IF (1:50-200) IP (1:20-50) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human ABRAXAS1
Purification	affinity purified by Protein A
Predicted MW.	47 kDa
Observed MW.	47 kDa
Subcellular Location	Nucleus
Gene ID	84142
Swiss-Prot	Q6UWZ7
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.