Product Name	Recombinant Rabbit Anti-EGLN3 Monoclonal Antibody
Cat No.	SLA2407M
Chinese Name	脯氨酸羟化酶重组兔单抗
Alias	HIFP4H3; HIFPH3; PHD3; 2610021G09Rik; Hif-p4h-3; SM-20; PHD-3; EGLN3_HUMAN; EGLN3; Egl nine homolog 3; HPH-1; Hypoxia-inducible factor prolyl hydroxylase 3 (HIF-PH3 | HIF-prolyl hydroxylase 3 | HPH-3); Prolyl hydroxylase domain-containing protein 3 (PHD3); 1.14.11.-; EGLN3_MOUSE; EGLN3_RAT; Sm20; egl-9 family hypoxia inducible factor 3; egl nine homolog 3 (C. elegans); HIF prolyl hydroxylase 3
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	4B1
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) ICC/IF (1:50-200) IP (1:20-50) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human PHD3
Purification	affinity purified by Protein A
Predicted MW.	27 kDa
Observed MW.	30 kDa
Gene ID	112399
Swiss-Prot	Q9H6Z9
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Prolyl hydroxylase that mediates hydroxylation of proline residues in target proteins, such as PKM, TELO2, ATF4 and HIF1A.Target proteins are preferentially recognized via a LXXLAP motif. Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.