Product Name	Recombinant Rabbit Anti-Fadd Monoclonal Antibody
Cat No.	SLA1703M
Chinese Name	Fas死亡结构域相关蛋白重组兔单抗
Alias	Mort1/FADD; FADD_MOUSE; Fadd; FAS-associating death domain-containing protein; Mediator of receptor induced toxicity; Mort1; GIG3; IMD90; FADD_HUMAN; Growth-inhibiting gene 3 protein; Fas associated via death domain; Fas (TNFRSF6)-associated via death domain; Fas-associating protein with death domain; mediator of receptor-induced toxicity
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	6B5
React Species	Mouse
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) Flow-Cyt (1:50-100) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from mouse Fadd
Purification	affinity purified by Protein A
Predicted MW.	23 kDa
Observed MW.	27 kDa
Subcellular Location	Cytoplasm
Gene ID	14082
Swiss-Prot	Q61160
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.