Product Name	Recombinant Rabbit Anti-SPN Monoclonal Antibody
Cat No.	SLA0361M
Chinese Name	人CD43单克隆抗体
Alias	CD43; GALGP; GPL115; LEU-22; LSN; A630014B01Rik; Ly-48; Ly48; LEUK_HUMAN; SPN; Galactoglycoprotein (GALGP); Leukocyte sialoglycoprotein; Sialophorin; LEUK_MOUSE; B-cell differentiation antigen LP-3; Lymphocyte antigen 48 (Ly-48); sialophorin (gpL115, leukosialin, CD43); leukosialin
Host Species	Mouse
Isotype	IgG
Clonality	Monoclonal
Clone No.	3F12
React Species	Human
Applications	IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) ICC/IF (1:100-500) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human CD43
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	40 kDa
Observed MW.	110-135 kDa
Subcellular Location	Membrane
Gene ID	6693
Swiss-Prot	P16150
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.