Product Name	Recombinant Rabbit Anti-NFE2 Monoclonal Antibody
Cat No.	SLA2689M
Chinese Name	转录因子NF-E2重组兔单抗
Alias	NF-E2; NF-E2/P45; p45; p45NFE2; p45nf-e2; NFE2_HUMAN; NFE2; Leucine zipper protein NF-E2; Nuclear factor, erythroid-derived 2 45 kDa subunit; p45 NF-E2; NFE2_MOUSE; NFE2_RAT; nuclear factor, erythroid 2; nuclear factor (erythroid-derived 2), 45kD; nuclear factor (erythroid-derived 2), 45kDa
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	8D6
React Species	Human
Applications	WB (1:500-2000) Flow-Cyt (1:50-100) ICC/IF (1:50-200) IP (1:20-50) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human NFE2
Purification	affinity purified by Protein A
Predicted MW.	41 kDa
Observed MW.	46 kDa
Subcellular Location	Nucleus
Gene ID	4778
Swiss-Prot	Q16621
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.