Product Name	Recombinant Rabbit Anti-TMPRSS2 Monoclonal Antibody
Cat No.	SLA2146M
Chinese Name	丝氨酸蛋白酶10重组兔单抗
Alias	PRSS10; D16Ertd61e; TMPS2_HUMAN; TMPRSS2; Serine protease 10; 3.4.21.122; TMPS2_MOUSE; Epitheliasin; Plasmic transmembrane protein X; transmembrane serine protease 2; transmembrane protease, serine 2
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	7H2
React Species	Human,Mouse
Applications	WB (1:500-2000) IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human TMPRSS2
Purification	affinity purified by Protein A
Predicted MW.	54 kDa
Observed MW.	52 kDa
Gene ID	7113
Swiss-Prot	O15393
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Plasma membrane-anchored serine protease that cleaves at arginine residues.Participates in proteolytic cascades of relevance for the normal physiologic function of the prostate.(Microbial infection) Facilitates human coronaviruses SARS-CoV and SARS-CoV-2 infections via two independent mechanisms, proteolytic cleavage of ACE2 receptor which promotes viral uptake, and cleavage of coronavirus spike glycoproteins which activates the glycoprotein for host cell entry.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.