Product Name	Recombinant Rabbit Anti-PSENEN Monoclonal Antibody
Cat No.	SLA1982M
Chinese Name	早老素γ分泌酶2重组兔单抗
Alias	ACNINV2; MDS033; MSTP064; PEN-2; PEN2; 1700023M09Rik; RGD1312037; PEN2_HUMAN; PSENEN; Presenilin enhancer protein 2; PEN2_MOUSE; PSN2_RAT; Psen2; PS-2; 3.4.23.-; Ps2; Psnl2; PEN2_RAT; Liver regeneration-related protein LRRGT00140; presenilin enhancer, gamma-secretase subunit; presenilin enhancer 2 homolog (C. elegans)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	3D19
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:100-200) IHC-F (1:100-200) IF (1:100-200) Flow-Cyt (1:50-100) ICC/IF (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human PEN 2
Purification	affinity purified by Protein A
Predicted MW.	12 kDa
Observed MW.	13 kDa
Gene ID	55851
Swiss-Prot	Q9NZ42
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP.The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels (Probable). PSENEN modulates both endoproteolysis of presenilin and gamma-secretase activity.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.