Product Name	Recombinant Rabbit Anti-MGMT Monoclonal Antibody
Cat No.	SLA1445M
Chinese Name	O6甲基鸟嘌呤DNA甲基转移酶重组兔单抗
Alias	MGMT_HUMAN; MGMT; 6-O-methylguanine-DNA methyltransferase (MGMT); O-6-methylguanine-DNA-alkyltransferase; 2.1.1.63; O-6-methylguanine-DNA methyltransferase; methylated-DNA--protein-cysteine methyltransferase
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	3F8
React Species	Human
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human MGMT
Purification	affinity purified by Protein A
Predicted MW.	22 kDa
Observed MW.	20 kDa
Gene ID	4255
Swiss-Prot	P16455
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.