Product Name	Recombinant Rabbit Anti-GRM5 Monoclonal Antibody
Cat No.	SLA1327M
Chinese Name	促代谢型谷氨酸受体5重组兔单抗
Alias	GPRC1E; MGLUR5; PPP1R86; mGlu5; 6430542K11Rik; Glu5R; mGluR5b; GRM5_HUMAN; GRM5; GRM5_MOUSE; GRM5_RAT; glutamate metabotropic receptor 5; glutamate receptor, metabotropic 5; protein phosphatase 1, regulatory subunit 86
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	11B6
React Species	Human,Mouse,Rat
Applications	IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) Flow-Cyt (1:50-100) ICC/IF (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human mGluR5
Purification	affinity purified by Protein A
Predicted MW.	132 kDa
Observed MW.	150 kDa
Subcellular Location	Membrane
Gene ID	2915
Swiss-Prot	P41594
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.