Product Name	ITGB2 | Human CD18 Mouse mAb
Cat No.	SLM-30018M
Chinese Name	小鼠抗人CD18单克隆抗体
Alias	CD18; LAD; LCAMB; LFA-1; MAC-1; MF17; MFI7; ITB2_HUMAN; ITGB2; Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit beta; integrin subunit beta 2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); complement component 3 receptor 3 and 4 subunit
Host Species	Mouse
Isotype	Mouse IgG1, k
Clonality	Monoclonal
Clone No.	18F7
React Species	Human
Applications	IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) Flow-Cyt (1:50-100) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human CD18
Purification	affinity purified by Protein G
Concentration	1mg/ml
Predicted MW.	82 kDa
Observed MW.	90-95 kDa
Subcellular Location	Membrane
Gene ID	3689
Swiss-Prot	P05107
Storage	0.01M PBS (pH7.4). Store at 2-8℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.