Product Name	Recombinant Rabbit Anti-PER2 Monoclonal Antibody
Cat No.	SLA1024M
Chinese Name	节律蛋白2重组兔单抗
Alias	FASPS; FASPS1; mKIAA0347; mPer2; PER2_HUMAN; PER2; hPER2; Circadian clock protein PERIOD 2; KIAA0347; PER2_MOUSE; period circadian regulator 2; period (Drosophila) homolog 2; period homolog 2 (Drosophila); period circadian clock 2
Host Species	Rabbit
Isotype	IgG/Kappa
Clonality	Monoclonal
Clone No.	12B5
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human PER2
Purification	affinity purified by Protein A
Concentration	1mg/m
Predicted MW.	138 kDa
Observed MW.	137-150 kDa
Subcellular Location	Nucleus
Gene ID	8864
Swiss-Prot	O15055
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	PER2, a mammalian homologue of the Drosophila period gene, shares a 40% homology with PER1 including the protein dimerization PAS domain. PER2 is a circadian regulator that may act as a transcription factor. It behaves as a negative element in circadian transcriptional loop. PER2 does not appear to bind DNA, suggesting indirect transcriptional inhibition. Expression oscillates with a 24 hour rhythm in the suprachiasmatic nucleus (SCN) and the whole eyes. Oscillations are maintained under constant darkness and are responsive to changes of the light/dark cycles. There is a 4 hour time delay between PER1 and PER2 oscillations. The expression rhythms appear to originate from retina.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.