Product Name	Recombinant Rabbit Anti-BGLAP Monoclonal Antibody
Cat No.	SLA0343M
Chinese Name	骨钙素单克隆抗体
Alias	BGP; OC; OCN; Bglap2; Bgpr; Bgpra; OSTCN_BOVIN; BGLAP; Bone Gla protein (BGP); Gamma-carboxyglutamic acid-containing protein; OSTCN_HUMAN; OSTCN_PIG; OSTCN_RAT; bone gamma-carboxyglutamate protein; bone gamma-carboxyglutamate (gla) protein; osteocalcin; bone gla protein
Host Species	Mouse
Isotype	IgG
Clonality	Monoclonal
Clone No.	7A2
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human Osteocalcin
Purification	affinity purified by Protein A
Predicted MW.	11 kDa
Observed MW.	10 kDa
Subcellular Location	Secreted
Storage	0.01M PBS (pH7.4). Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Osteocalcin belongs to the osteocalcin/matrix Gla protein family and constitutes 1 to 2% of the total bone protein. It is a 49 amino acid single chain vitamin K dependent protein, made by osteoblasts, and is a major component of the noncollagenous bone matrix. Post translational modification by a vitamin K dependent carboxylase produces three gamma carboxyglutamic acid residues at positions 17, 21 and 24, giving it a high affinity for calcium. It also binds strongly to apatite.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. 25 ug total protein per lane of various lysates (see on figure) probed with Osteocalcin monoclonal antibody, unconjugated (SLA0343M) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.