Product Name	UCP1 Rabbit pAb
Cat No.	SL42259R
Chinese Name	线粒体脱偶连蛋白1抗体
Alias	SLC25A7; UCP; Ucpa; Uncp; UCP1_HUMAN; UCP1; UCP 1; Solute carrier family 25 member 7; Thermogenin; UCP1_MOUSE; UCP1_RAT; uncoupling protein 1; uncoupling protein 1 (mitochondrial, proton carrier)
Host Species	Rabbit
Isotype	IgG
Clonality	Polyclonal
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant human UCP1 protein
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	33 kDa
Observed MW.	35 kDa
Subcellular Location	Cytoplasm
Gene ID	7350
Swiss-Prot	P25874
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq].
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Sample: Lane 1: Recombinant human UCP1 protein, His(SL42259P) Primary: Anti-UCP1 (SL42259R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 33 kDa Observed band size: 35 kDa

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.