Product Name	TNFRSF10A | DR4/TRAILR1/CD261 Rabbit pAb
Cat No.	SL42079R
Chinese Name	死亡受体4抗体
Alias	APO2; CD261; DR4; TRAILR-1; TRAILR1; TR10A_HUMAN; TNFRSF10A; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1 (TRAIL receptor 1 | TRAIL-R1); TNF receptor superfamily member 10a; tumor necrosis factor receptor superfamily, member 10a
Host Species	Rabbit
Isotype	IgG
Clonality	Polyclonal
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant human DR4 protein
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	48 kDa
Observed MW.	23 kDa
Subcellular Location	Membrane
Gene ID	8797
Swiss-Prot	O00220
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Sample: Lane 1: Recombinant human DR4 protein, C-His(SL42079P) Primary: Anti-TNFRSF10A (SL42079R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 48 kDa Observed band size: 23 kDa

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.