Product Name	Recombinant Rabbit Anti-PGA4 Monoclonal Antibody
Cat No.	SLA0499M
Chinese Name	胃蛋白酶原4单克隆抗体
Alias	pepsinogen A4; pepsinogen 4, group I (pepsinogen A); pepsin A; Pepsin A-4; PEPA4_HUMAN; PGA4; pepsinogen 4, group I(pepsinogen A); Pepsin A 4; Pepsinogen-4
Host Species	Mouse
Isotype	IgG
Clonality	Monoclonal
Clone No.	8E1
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant human PGA4 protein
Purification	affinity purified by Protein A
Predicted MW.	42 kDa
Observed MW.	42 kDa
Subcellular Location	Cytoplasm
Storage	Size : 50ul/100ul/200ul 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Size : 200ug (PBS only) 0.01M PBS (pH7.4). Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity, and although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. The amino acid composition of Pepsin C differs from those of pepsinogen and pepsin especially in the content of basic amino acids, glutamic acid, aspartic acid, leucine and isoleucine.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Sample: Lane 1: Recombinant human Pepsin A-4 / PGA4 protein, His(SL41228P) Primary: Anti-PGA4 (SLA0499M) at 1/1000 dilution Secondary: Alexa Fluor 790 AffiniPure Goat Anti-Mouse IgG, light chain specific Predicted band size: 42 kDa Observed band size: 42 kDa

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.