Product Name	Rabbit Anti-AR Polyclonal Antibody
Cat No.	SLA0014
Chinese Name	磷酸化雄激素受体（AR）抗体
Alias	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM; Andr; ANDR_HUMAN; AR; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4; ANDR_MOUSE; ANDR_RAT; androgen receptor; spinal and bulbar muscular atrophy; testicular feminization; Kennedy disease; AR | Androgen receptor (phospho-S791); p-Androgen receptor; phospho-Androgen receptor; p-AR; AR | Androgen receptor (phospho-Ser791)
Host Species	Rabbit
Isotype	IgG
Clonality	Polyclonal
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human Androgen receptor isoform 2
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	98 kDa
Observed MW.	115 kDa
Gene ID	367
Swiss-Prot	P10275
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Sample: Lane 1: Mouse Testis tissue lysates Lane 2: Rat Testis tissue lysates Lane 3: Human MCF-7 cell lysates Primary: Anti-phospho-AR/Androgen receptor (Ser791) (SLA0014) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 98 kDa Observed band size: 115 kDa

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.