Product Name	Recombinant Rabbit Anti-SLC7A11 Monoclonal Antibody
Cat No.	SLA1661M
Chinese Name	钙离子通道阻端耐药蛋白CCBR1重组兔单抗
Alias	XCT_HUMAN; SLC7A11; Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; Solute carrier family 7 member 11; xCT; CCBR1; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	11H12
React Species	Human,Mouse,Rat
Applications	WB (1:1000-2000) IP (1:50-100) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human xCT
Purification	affinity purified by Protein A
Predicted MW.	55 kDa
Observed MW.	60 kDa
Subcellular Location	Membrane
Gene ID	23657
Swiss-Prot	Q9UPY5
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Heterodimer with SLC3A2, that functions as an antiporter by mediating the exchange of extracellular anionic L-cystine and intracellular L-glutamate across the cellular plasma membrane.Provides L-cystine for the maintenance of the redox balance between extracellular L-cystine and L-cysteine and for the maintenance of the intracellular levels of glutathione that is essential for cells protection from oxidative stress.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. 25 ug total protein per lane of various lysates (see on figure) probed with CCBR1 monoclonal antibody, unconjugated (SLA1661M) at 1:2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.