Product Introduction:

Amyloid is a kind of extracellular acidophilic substance with no fixed shape, which can exist in different tissues and organs, resulting in diseases called amyloidosis. Amyloid is mainly composed of proteins, most of which are arranged in reverse β - fold structure. Under the electron microscope, the amyloid materials are arranged as fibrils. In the case materials, there are a large number of non branching filaments, most of which are randomly arranged. The histological methods for the identification of amyloid substances include Violet Staining, Congo Red Staining and polarized light microscopy. At present, research has found that the traditional methyl violet staining method has low sensitivity and poor specificity. The classic and effective method is Congo red staining.In 1922, Bennhold found that Congo red can be used to identify starch like substances in vivo, and applied to tissue sections.
Congo Red Stain Solution, 1% is a ready-to-use solution that can be used to stain starch like substance in tissue sections.The principle of Congo Red Stain Solution, 1% is that amyloid has a greater affinity for Congo red than other tissue structures, and its hydroxyl group combines with the amino group of Congo red to make amyloid red.

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