Product Introduction:

Nissl bodies are small triangular or oval shaped substances distributed in the cytoplasm of nerve cells, which can be dyed purple blue by alkaline dyes such as thionine, methylene blue, toluidine blue, and tar violet. Various nerve cells contain Nissl bodies, but their shape, quantity, and distribution often vary. Nissl bodies also exist in dendrites, but not in axons and axonomes. The Nissl body is an important site for protein synthesis in neurons. When neurons are stimulated, the Nissl body in the cell is significantly reduced.
The import tar violet is used as the core dye in Tar Violet Aqueous Solution, 0.06%, Water Solvent. Cresyl violet had photosensitive effect and could well show the change of Nissl body. It can be used to stain Nissl substance and neurons in paraffin or frozen sections. The existence and disappearance of Nissl body is an important indicator of whether nerve cells are damaged. When encephalitis, cerebral ischemia, axon reaction and other conditions occur, Nissl body will dissolve or even disappear.

Note：Product information may be optimized and upgraded. Please refer to the actual label information for accuracy.

Experiment picture

Paraffin section of mouse brain
Nissl bodies stain violet-blue; background stains light blue or nearly colorless.

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