Product Introduction:

Myelin sheath is a layer of membrane wrapped outside the axons of nerve cells, that is, myelin sheath is composed of myelin cells and cell membrane. It is a multilayer lipid double-layer structure formed by the plasma membrane of nerve cells spirally winding along the axis of axon. There is Langfei's node on the myelin sheath, which can make the nerve impulse and jump to transmit. Myelin staining has certain significance in pathological diagnosis. The pathological changes of myelin sheath can be divided into early, middle and late stages. In the early stage of the lesion, the color is deep. In the middle stage, the myelin degenerated into lipid droplets, which can be displayed by lipid staining. In the late stage, the myelin sheath degenerated completely and is cleared by phagocytes, so there is no positive result of myelin sheath.
Many diseases can cause the change of myelin sheath. Luxol Fast Blue Myelin Staining can show whether the myelin sheath is complete, denatured, necrotic and repaired under pathological conditions. It has significance for the pathological diagnosis and research of nerve tissue. For example, when the nerve fiber is damaged, the myelin sheath can appear expansion, zigzag into a sphere, break or completely disappear without sheath.

Note：Product information may be optimized and upgraded. Please refer to the actual label information for accuracy.

Experiment picture

Paraffin section of mouse brain
Myelin sheaths stain blue-green; background is colorless or light blue.

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