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Product Name DEFB135 Chinese Name 防御素β-135/β-defensin 135抗体 Alias beta 135; Beta-defensin 135; DB135_HUMAN; DEFB135; Defensin; Defensin, beta 135. Research Area Cell biology immunology Bacteria and viruses Extracellular matrix Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 6.1kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human DEFB135: 25-77/77 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Beta-defensins are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. The family of Beta-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many Beta-defensins are also involved in sperm maturation and capacitation. Beta-defensin 135, also designated Beta-defensin 136, is a 77 amino acid member of the Beta-defensin protein family. Beta-defensin 135 is a secreted protein believed to have antibacterial activity.
Function:
Has antibacterial activity.
Subcellular Location:
Secreted.
Similarity:
Belongs to the beta-defensin family.
SWISS:
Q30KP9
Gene ID:
613209
Database links:Entrez Gene: 613209 Human
SwissProt: Q30KP9 Human
Unigene: 558284 Human
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