Product Name	DEXI
Chinese Name	地塞米松诱导蛋白DEXI抗体
Alias	Dexamethasone-induced protein; DEXI; DEXI_HUMAN; MYLE; Protein MYLE.
Research Area	Cell biology immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse(predicted:Human,Rat,Cow,Horse,Sheep)
Applications	IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	10kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DEXI: 51-95/95
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	DEXI is a 95 amino acid protein belonging to the DEXI family. Induced by dexamethasone, DEXI is expressed in brain, liver, pancreas, placenta and lung, with highest levels in heart. DEXI is also up-regulated in emphysematous lung compared to normal lung. The gene encoding DEXI maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition. Tissue Specificity: Highest levels in heart. Also expressed in brain, liver, pancreas, placenta and lung. Up-regulated in emphysematous lung compared to normal lung. Similarity: Belongs to the DEXI family. SWISS: O95424 Gene ID: 28955 Database links: Entrez Gene: 28955 Human Entrez Gene: 58239 Mouse SwissProt: O95424 Human SwissProt: Q9WUQ7 Mouse Unigene: 592051 Human
Product Picture	Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DEXI) Polyclonal Antibody, Unconjugated (SL14283R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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