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Rabbit Anti-RHD Polypeptide antibody

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  • Cat NO.:SL20221R
  • Product Spec:100ul
  • Clonality:Polyclonal
  • 100ul:263.00$
  • 200ul:413.00$
  • Price:$263
  • Total:
  • Quantity:
  • Manual

Goods Brief:

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Product Name RHD Polypeptide
Chinese Name Rh polypeptide 2抗体
Alias Blood group Rh(D) polypeptide; Blood group--Rhesus system D polypeptide; CD240D; D antigen (DCS); DIIIc; MGC165007; RH; Rh blood group antigen Evans; Rh blood group D antigen; Rh polypeptide 2; RH30; Rh4; RHCED; Rhd; RHD_HUMAN; RhDCw; RHDel; RHDVA(TT); Rhesus blood group D antigen allele DIII type 7; Rhesus D antigen; Rhesus system D polypeptide; RhII; RhK562-II; RhPI.  
Organism Species Rabbit
Clonality Polyclonal
React Species Human, 
Applications ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 45kDa
Cellular localization The cell membrane 
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human RHD Polypeptide:21-120/417 
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
Product Detail The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.

Subcellular Location:
Membrane.

Tissue Specificity:
Restricted to tissues or cell lines expressing erythroid characters.

Similarity:
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.

SWISS:
Q02161

Gene ID:
6007

Database links:

Entrez Gene: 6007 Human

Omim: 111680 Human

SwissProt: Q02161 Human

Unigene: 449968 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.