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Mouse Anti-GABARAP antibody

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  • Cat NO.:SLM51134M
  • Product Spec:50ul
  • Clonality:Monoclonal
  • 50ul:143.00$
  • 100ul:263.00$
  • Price:$143
  • Total:
  • Quantity:
  • Manual

Goods Brief:

Product Name GABARAP
Chinese Name 小鼠抗γ-氨基丁酸受体相关蛋白单克隆抗体
Alias ATG8A; FLC 3B; FLC3B; FLJ25768; GABA(A) receptor associated protein; GABA(A) receptor-associated protein; GABARAP a; GABARAP; Gamma aminobutyric acid receptor associated protein; Gamma-aminobutyric acid receptor-associated protein; GBRAP_HUMAN; MGC120154; MGC120155; MM 46; MM46.  
Organism Species Mouse
Clonality Monoclonal
克 隆 号 10B2
React Species Human, Mouse, Rat, Cow, Rabbit, 
Applications WB=1:500-2000 ELISA=1:500-1000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 14kDa
Cellular localization cytoplasmic The cell membrane 
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen Recombinant human GABARAP protein: 
Lsotype IgG1
Purification affinity purified by Protein G
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
Product Detail Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. [provided by RefSeq, Jul 2008]

Function:
May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton.

Subunit:
Interacts with GPHN and NSF. Interacts with GABRG2, beta-tubulin and ULK1. Interacts with CALR. Interacts with DDX47. Interacts with TP53INP1 and TP53INP2. Interacts with TBC1D25.

Subcellular Location:
Endomembrane system. Cytoplasm, cytoskeleton. Golgi apparatus membrane. Largely associated with intracellular membrane structures including the Golgi apparatus and post-synaptic cisternae. Colocalizes with microtubules.

Tissue Specificity:
Heart, brain, placenta, liver, skeletal muscle, kidney and pancreas.

Similarity:
Belongs to the MAP1 LC3 family.

SWISS:
O95166

Gene ID:
11337

Database links:

Entrez Gene: 11337 Human

Entrez Gene: 56486 Mouse

Entrez Gene: 58974 Rat

Omim: 605125 Human

SwissProt: O95166 Human

SwissProt: Q9DCD6 Mouse

SwissProt: P60517 Rat

Unigene: 647421 Human

Unigene: 272460 Mouse

Unigene: 8411 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
 
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