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Product Name SLC38A5 Chinese Name 溶质载体Transporter家族38成员A5抗体 Alias Amino acid transporter system N2; JM 24; JM24; pp7194; S38A5; S38A5_HUMAN; Slc38a5; SLC8 A5; SLC8A 5; SN 2; SN2; SNAT 5; SNAT5; Sodium coupled neutral amino acid transporter 5; Sodium coupled neutral amino acid transporter5; Sodium-coupled neutral amino acid transporter 5; Solute carrier family 38 member 5; Solute carrier family 38 member5; System N transporter 2; System N transporter2. Organism Species Rabbit Clonality Polyclonal React Species Human, Mouse, Rat, Applications ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 52kDa Cellular localization The cell membrane Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SLC38A5:401-472/472 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Storage Buffer Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed PubMed Product Detail The protein encoded by this gene is a system N sodium-coupled amino acid transporter. The encoded protein transports glutamine, asparagine, histidine, serine, alanine, and glycine across the cell membrane, but does not transport charged amino acids, imino acids, or N-alkylated amino acids. Alternative splicing results in multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Aug 2013]
Function:
Functions as a sodium-dependent amino acid transporter which countertransport protons. Mediates the saturable, pH-sensitive, and electrogenic cotransport of several neutral amino acids including glycine, asparagine, alanine, serine, glutamine and histidine with sodium.
Subcellular Location:
Cell membrane.
Tissue Specificity:
Predominantly expressed in stomach, brain, liver, lung and intestinal tract.
Similarity:
Belongs to the amino acid/polyamine transporter 2 family.
SWISS:
Q8WUX1
Gene ID:
92745
Database links:Entrez Gene: 92745 Human
Entrez Gene: 209837 Mouse
Omim: 300649 Human
SwissProt: Q8WUX1 Human
SwissProt: Q3U1J0 Mouse
Unigene: 195155 Human
Unigene: 6055 Mouse
Unigene: 81033 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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