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Rabbit Anti-Histamine antibody

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  • Cat NO.:SL2325R
  • Product Spec:100ul
  • Clonality:Polyclonal
  • 100ul:263.00$
  • 200ul:413.00$
  • Price:$263
  • Total:
  • Quantity:
  • Manual

Goods Brief:

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Product Name Histamine
Chinese Name 组胺Histamine多克隆抗体
Organism Species Rabbit
Clonality Polyclonal
React Species Histamine
Applications ELISA=1:500-1000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Cellular localization Secretory protein 
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated Histamine: 
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
Product Detail Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. Histamine is involved in the inflammatory response and has a central role as a mediator of pruritus. As part of an immune response to foreign pathogens, histamine is produced by basophils and by mast cells found in nearby connective tissues. Histamine increases the permeability of the capillaries to white blood cells and some proteins, to allow them to engage pathogens in the infected tissues.

Subunit:
Histamine has two basic centres, namely the aliphatic amino group and whichever nitrogen atom of the imidazole ring does not already have a proton. Under physiological conditions, the aliphatic amino group (having a pKa around 9.4) will be protonated, whereas the second nitrogen of the imidazole ring (pKa ≈ 5.8) will not be protonated. Thus, histamine is normally protonated to a singly charged cation.

SWISS:
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Gene ID:
51-45-6

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.