Cytochalasin E

Product introduction

Cytorelaxin is a fungal metabolite that inhibits actin polymerization through cells.

Molecular formula: C28H33NO7, molecular weight: 495.56

Physical properties and indexes:

Appearance: …………………… White crystalline powder

Melting point: …………………… 205 ~ 210 ° C

Solubility: ………………… Soluble in DMSO(10mg/ml), ethanol (2mg/ml)

Burning residue: ……………… < 0.1%

Purity: …………………… > 98%

Biological activity:

The cytochalasins are cell-permeable fungal metabolites which inhibit actin polymerization. This interferes with such  diverse processes as cell movement, growth, phagocytosis, degranulation,  and secretion. Cytochalasin E is an epoxide-containing analog of cytochalasin B which potently and selectively inhibits  the growth of endothelial cells (IC50 < 1 nM),  impairing angiogenesis and tumor growth. This cytochalasin does not inhibit glucose transport or HIV-1 protease  activity.

Use and description: scientific research reagent

Storage conditions:

 

15 ~ 20 ° C

 

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